TRiCAM Director and Professor of Psychology
Education/Degrees
Post-Doctoral Fellowship, Clinical Cognitive Neuroscience Laboratory, Western Psychiatric Institute & Clinic, Department of Psychiatry University of Pittsburgh Medical Center, 2002
Ph.D. in Clinical Psychology, University of Pittsburgh, 2001
B.A. in Psychology and Philosophy, Amherst College, 1990
Research Interests
Basic cognitive and affective neuroscience using fMRI, the neural and genetic bases of schizophrenia and other mental illnesses, and the psychometrics of measuring group differences
Selected Publications
- MacDonald, A. W. III, Patzelt, E., Kurth-Nelson, Z., Barch, D. M., Carter, C. S., Gold, J. M., Ragland, J. D., & Silverstein, S. M. (2025). Computational modeling of reversal learning impairments in schizophrenia and bipolar disorder reveals shared failure to exploit rewards. Journal of Psychopathology and Clinical Science, 134(3), 262–271. https://doi.org/10.1037/abn0000944
- MacDonald, A.W., III & Demro, C. (2023). Schizophrenia: Presentation, Affect and Cognition, Pathophysiology & Etiology. In Blaney, P., Krueger, R.F. (Eds.) Oxford Textbook of Psychopathology. New York: Oxford University Press.
- Kazinka, R., Vilares, I., & MacDonald, A. W. (2022). A Computational Model of Non-optimal Suspiciousness in the Minnesota Trust Game. Computational Psychiatry, 6(1), 60–78. https://doi.org/10.5334/cpsy.82
- MacDonald III, A. W., Zick, J. L., Netoff, T. I., & Chafee, M. V. (2022). The Computation of Collapse. Computational Psychiatry: New Perspectives on Mental Illness, 20, 153.
- Ma, Y., & MacDonald III, A. W. (2021). Impact of Independent Component Analysis Dimensionality on the Test–Retest Reliability of Resting-State Functional Connectivity. Brain Connectivity, 11(10), 875–886. https://doi.org/10.1089/brain.2020.0970
- Poppe, A. & MacDonald, A.W., III (2019). Cognitive Neuroscience Approaches to Personality Disorders. In C. Schmahl, K.L. Phan, R.O. Friedel, and L.J. Siever (Eds.), Neurobiology of Personality Disorders. NY NY: Oxford University Press, pp. 75-94.
- MacDonald, A.W., III, Zick, J.I., Chafee, M.V., Netoff, T.I. (2016). Integrating insults: Using fault tree analysis to guide schizophrenia research across levels of analysis. Frontiers of Human Neuroscience, 9, 698. PMID: 26779007
- Goghari, V., MacDonald, A.W., III, Sponheim, S.R. (2011). Temporal lobe structures and facial emotion recognition in schizophrenia patients and non-psychotic relatives. Schizophrenia Bulletin, 37, 1281-1284. doi: 10.1093/schbul/sbq046 PMCID: 3196942
- Kerns, J.G., Cohen, J.D., MacDonald, A.W, III, Johnson, M.K., Stenger, V.A., Aizenstein, H.J., Carter, C.S. (2005). Decreased conflict and error-related activity in the anterior cingulate cortex in schizophrenia. American Journal of Psychiatry, 162, 1833-1839. PMID:16199829
- MacDonald, A.W., III, Carter, C.S., Kerns, J.G., Ursu, S., Barch, D.M., Holmes, A.J., Stenger, V.A., & Cohen, J.D. (2005). Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis. American Journal of Psychiatry, 162, 475-84. PMID: 15741464
- Snitz, B.E., MacDonald, A.W., III, Cohen, J.D., Becker, T., Carter, C.S. (2005). Lateral and medial hypofrontality in first-episode schizophrenia: Functional activity in a medication-naïve state and effects of short-term atypical antipsychotic treatment. American Journal of Psychiatry, 162, 2322-2329. PMID: 16330597
- Kerns, J.G., Cohen, J.D., MacDonald, A.W., III, Cho, R.Y., Stenger, V.A., & Carter, C.S. (2004). Anterior cingulate conflict monitoring and adjustments in control. Science, 303, 1023-1026. PMID:14963333
- MacDonald, A.W., III, & Carter, C.S. (2003). Event-related fMRI study of context processing in the dorsolateral prefrontal cortex of patients with schizophrenia. Journal of Abnormal Psychology, 112, 689-697. PMID: 14674880
- MacDonald, A.W., III, Pogue-Geile, M.F, Johnson, M.K. & Carter, C.S (2003). A specific deficit in context processing in the unaffected siblings of patients with schizophrenia. Archives of General Psychiatry, 60, 57-65. PMID: 12511173
- MacDonald, A.W., III, & Carter, C.S. (2002). Cognitive experimental approaches to investigating impaired cognition in schizophrenia: a paradigm shift. Journal of Experimental and Clinical Neuropsychology, 24, 873-882. PMID: 12647766
- Carter, C.S., MacDonald, A.W., III, Ross, L.L., Stenger, V.A. (2001). Anterior cingulate cortex and impaired self-monitoring of performance in schizophrenia: an event-related fMRI study. American Journal of Psychiatry, 158, 1423-1428. PMID: 11532726
- MacDonald, A.W., III, Pogue-Geile, M.F., Debski, T.T., & Manuck, S. (2001). Genetic and environmental influences on schizotypy: A community-based twin study. Schizophrenia Bulletin, 27, 47-58. PMID: 11215549
- MacDonald, A.W., III, Cohen, J.D., Stenger, V.A., & Carter, C.S. (2000). Dissociating the role of the dorsolateral prefrontal cortex and anterior cingulate cortex in cognitive control. Science, 288, 1835-1838. PMID: 1084616
Contact Information
612-624-3813