Grants

Current Grants

  1. P50 Conte Center National Institute of Mental Health, “PROJECT 4: Characterizing the course of state representation in early psychosis.” Part of the P50 Center Dysfunctional State Representations in Psychosis: From Neurophysiology to Neuroplasticity-based Treatment. $9,750,000 direct costs. A.W. MacDonald, III, Scott Sponheim, Project 4 Co-Principal Investigators. Sophia Vinogradov & A. David Redish, Center PI’s. June 2025–May 2030 (P50MH119569)
  2. R01 National Institute of Mental Health, “Rule-Based Decision-Making: A Transdiagnostic Neuroeconomic Mechanism of Anorexia Nervosa and Related Disorders” $1,750,000 direct costs. A.W. MacDonald, III, Co-Investigator. Annie Haynos, PI. September 2022–May 2027 (R01MH126978)

Past Grants

  1. R01 National Institute of Mental Health, “5/5 Cognitive Neurocomputational Task Reliability & Clinical Applications.” $1,500,000 direct costs current cycle. A.W. MacDonald, III, Principal Investigator. September 2019–June 2024 (R01MH084861) No Cost Extension to June 2026

  2. NeuroPRSMH Seed Grant, “Non-invasive scalable method for improving cognitive flexibility.” $100,000 direct costs. A.W. MacDonald, III, Co-Investigator. Michael Bronstein, PI. January 2024–January 2025.

  3. NIH RF1 BRAIN Initiative, "Increased thalamocortical connectivity in tdcs-potentiated generalization of cognitive training." $1,990,000 direct costs. A.W. MacDonald, III and K.O. Lim, Multiple PIs. August 2018–May 2023 NCE (RF1MH116987)

  4. R21 National Institute of Mental Health, “Computational dissociation of the causes of cognitive rigidity in depression.” $275,000 direct costs. A.W. MacDonald, III, Co-Investigator. Alex Herman, PI. June 2021–May 2023. (R21MH127607)
  5. R21 National Institute of Mental Health, “Parametrically Detailed Computational Analyses of Human Foraging Behavior.” A.W. MacDonald, III, Co-Investigator. $275,000 direct costs. Alik Widge, Principal Investigator. July 2019–June 2022 (R21MH120785)
  6. Merit Review, Department of Veterans Affairs. “Restoration of cognitive function with TDCS and training in schizophrenia.” $749,000 direct costs. Tasha Nienow, Principal Investigator. A.W. MacDonald, III, Co-Investigator. July 2017–June 2022
  7. R21 National Institute of Mental Health, “Persecution in RDoC: Spite Sensitivity and Frontal Dysconnectivity.” $250,000 direct costs. A.W. MacDonald, III, Principal Investigator. August 2017–July 2019, NCE (R21MH112918)
  8. National Institute of Mental Health, “Neural Disconnection and Errant Visual Perception in Psychotic Psychopathology.” $1,025,000 direct costs. Scott Sponheim, Principal Investigator, Angus W. MacDonald, III, Co-investigator. September 2016–August 2020, NCE (U01MH108150)
  9. University of Minnesota Informatics Institute, On the Horizon Award, “Human Connectome Project (HCP) Hosting at the Minnesota Supercomputer Institute (MSI).” $25,700 direct costs. A.W. MacDonald, III, Principal Investigator. January 2016–August 2019.
  10. R01 National Institute of Mental Health, “Cognitive Neuroscience Task Reliability & Clinical Applications.” $600,000 direct costs current cycle. A.W. MacDonald, III, Principal Investigator. September 2008–April 2018 (R01MH084861).
  11. National Institute of Mental Health, National Research Service Award F31, “Translating from Rats to Humans: A Human Foraging Model of Decision-Making.” Samantha Abram, Trainee. A.W. MacDonald, III, Advisor and Co-Investigator. July 2015–June 2017 (F31DA040335).
  12. University of Minnesota College of Liberal Arts Brain Imaging Project, “Foraging Decisions: Value and Experiential Processing in Salience, Control and Reward Networks.” $10,000 pilot funds. A.W. MacDonald, III, Principal Investigator. June 2015–June 2016.
  13. R21 National Institute of Mental Health, “The Eye: A Window on Schizophrenia.” $275,000 direct costs. R. Miller, Principal Investigator. A.W. MacDonald, III, Co-Investigator and Project Director. April 2013–February 2016 (R21MH100622).
  14. R01 National Institutes of Health. “Psychological and Cognitive Mechanisms Underlying Sexual Compulsivity and HIV Risk.” $818,000 direct costs. M. Miner, Principal Investigator. A.W. MacDonald, III, Co-Investigator. July 2011–November 2014 (R01MH094229).
  15. Merit Review, Clinical Science Research and Development, Department of Veterans Affairs.“Genetic and time-frequency aspects of neural phenotypes in schizophrenia.” $650,000 direct costs. S.R. Sponheim, Principal Investigator. A.W. MacDonald, III, Co-Investigator. April 2010–March 2014.
  16. Merit Review, Department of Veterans Affairs. “Remediation of working memory in schizophrenia.” $750,000 direct costs. Tasha Nienow, Principal Investigator. A.W. MacDonald, III, Co-Investigator. January 2010–December 2013.
  17. R21 National Institute of Drug Abuse, “Neuroanatomical basis of anti-drug message processing.” $750,000 direct costs. A.W. MacDonald, III & M.C. Yzer, Co-Principal Investigators. September 2007–April 2013 (R21DA024430).
  18. R01 National Institute of Mental Health. “Cognitive Neuroscience Task Reliability & Clinical Applications.” $200,000 additional direct costs. A.W. MacDonald, III, Principal Investigator. Multi-site study. ARRA-funded Competitive Revision of R01MH084861. July 2010–June 2012 (R01MH084861-03S1).
  19. R21 National Institute of Mental Health. “Imaging the impact of glutamate liability genes in schizophrenia.” $275,000 direct costs. A.W. MacDonald, III, Principal Investigator. February 2008–November 2011 (R21MH079262).
  20. R01 National Institute of Mental Health, “White Matter Abnormalities in Schizophrenia“ $2,500,000 total direct costs. K.O. Lim, Principal Investigator, A.W. MacDonald, III, Co-Investigator. October 2005–September 2010. (R01MH060662).
  21. P20 National Institute of Drug Abuse, “Center for the Study of Impulsivity in Addiction.” $2,000,000 total direct costs, $200,000 direct core costs. K.O. Lim, Principal Investigator. A.W. MacDonald, III, Director of the Cognitive and Behavioral Core. September 2007–June 2012 (P20DA024196).
  22. National Alliance for Research in Schizophrenia and Affective Disorders (NARSAD), Young Investigator and Francoeur Investigator Awards. “The Neural Basis of Paranoia in Schizophrenia” $60,000 direct costs. A.W. MacDonald, III, Principal Investigator. July 2008–June 2010.
  23. Merit Review, Department of Veterans Affairs. “Neural Phenotype-Genotype Associations in Schizophrenia.” $799,400 total direct expenses, approx $200,000 total site specific direct costs. S.R. Sponheim, Principal Investigator, A.W. MacDonald, III, Co-Investigator and Site Project Director. April 2005–March 2010.
  24. R01 National Institute of Mental Health, “Cognitive Neurogenetics of Schizophrenia.” $1,000,000 direct expenses, approx. $140,000 total site specific direct costs. C.S. Carter, Principal Investigator, A.W. MacDonald, III, Co-Investigator. December 2003–November 2008 (R01MH066629).
  25. National Alliance for Research in Schizophrenia and Affective Disorders (NARSAD), Young Investigator Award. “The Genetic and Neural Basis of Paranoia: A Functional MRI Study in Twins.” $60,000 total direct costs. A.W. MacDonald, III, Principal Investigator. July 2005–June 2007.
  26. R24 National Institute of Mental Health, “Aberrant Cortical Dynamics in Schizophrenia.” $725,000 total direct expenses, approx. $142,000 total site specific direct costs. S.R. Sponheim, Principal Investigator, A.W. MacDonald, III, Co-Investigator and Site Project Director. July 2004–June 2007 (R24MH069675).
  27. Clinical Research Feasibility Funding (CReFF). University of Minnesota General Clinical Research Center. “Changes in Cortical Activation with Cognitive Rehabilitation in Schizophrenia.” $40,000 total direct costs. A.W. MacDonald, III, Principal Investigator. December 2003–November 2005.
  28. Grant-in-Aid of Research, Artistry and Scholarship, University of Minnesota, “Advanced Methods for Dissociating Cognitive Control Mechanisms in fMRI.” $25,000 total direct costs. A.W. MacDonald, III, Principal Investigator. July 2003–December 2005.
  29. NCRR, Biomedical Informatics Research Network (BIRN). “Functional Imaging Research in Schizophrenia Testbed – FIRST BIRN.” $1,000,000 total site specific direct costs. S.G. Potkin, Principal Investigator, K.O. Lim, Site Project Director, A.W. MacDonald, III, Co-Investigator. October 2002–November 2005.