Selected Publications

2018

Kang, S.S., MacDonald, A.W., III, Chafee, M.V., Im, C-H, Bernat, E.M., Davenport, N.D., Sponheim, S.R. (in press). Aberrant Cortical Neural Synchrony During Working Memory in Schizophrenia. Clinical Neurophysiology.

Feuerstahler, L., Luck, S., MacDonald, A.W., III, Waller, N. (in press). A Note on the Identification of Change Detection Task Models to Measure Storage Capacity and Attention in Visual Working Memory. Behavior Research Methods. [CNTRACS]

Rueter, A., Abram, S., MacDonald, A.W., III, Rusticini, A. & DeYoung, C. (in press). The Goal Priority Network as a Neural Substrate of Conscientiousness. Human Brain Mapping.

Sweis, B. M., Abram, S. V., Schmidt, B. J., Seeland, K. D., MacDonald, A. W., Thomas, M. J., & Redish, A. D. (2018). Sensitivity to "sunk costs" in mice, rats and humans. Science, 361, 178-181.DOI: 10.1126/science.aar8644.

2017

Abram, S.V., Wisner, K.M., Fox, J.M., Barch, D.M., Wan, L., Csernansky, J.G., MacDonald, A.W., III, Smith, M.J. (2017). Fronto-Temporal Connectivity Predicts Cognitive Empathy Deficits and Experiential Negative Symptoms in Schizophrenia. Human Brain Mapping, 38, 1111-1124. PMID: 27774734

Barch, D.M., Carter, C.S., Gold, J.M., Johnson, S.L., Kring, A.M., MacDonald, A.W., III, Pizzagalli, D.A., Ragland, J.D., Silverstein, S.M., Strauss, M.E. (2017). Explicit and implicit reinforcement learning across the psychosis spectrum. Journal of Abnormal Psychology, 126, 694-711. PMCID: PMC5503766 [CNTRACS]

Ermel J., Carter C.S., Gold J.M., MacDonald A.W., III, Ragland J.D., Silverstein S.M., Strauss M.E., Barch D.M. (2017). Self versus informant reports on the specific levels of functioning scale: Relationships to depression and cognition in schizophrenia and schizoaffective disorder. Schizophr Res Cognition, 9, 1-7. PMID: 28740827 [CNTRACS]

Mervis, J.E., Capizzi, R., Boroda, E., MacDonald, A.W., III. (2017). Transcranial Direct Current Stimulation over the Dorsolateral Prefrontal Cortex in Psychosis: A Quantitative Review of Cognitive Outcomes. Frontiers in Human Neuroscience. Included in the ebook, Revisiting the Effectiveness of Transcranial Direct Current Brain Stimulation for Cognition: Evidence, Challenges, and Open Questions, E.G. Chrysikou , M.E. Berryhill , M. Bikson & H.B. Coslett. PMID: 28210217

Ramsay, I.S., Nienow, T. M., & MacDonald, A.W., III. (2017). Increases in Intrinsic Thalamocortical Connectivity and Overall Cognition Following a Randomized Controlled Trial of Cognitive Remediation in Schizophrenia. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2, 355–362. PMCID: PMC5455781

Ramsay, I.S., Nienow, T. M., & MacDonald, A.W., III. (2017). Neuroplastic changes in patients with schizophrenia undergoing cognitive remediation: triple-blind trial. British Journal of Psychiatry, 210, 216-222. PMCID: PMC5331188

Ray K.L., Lesh T.A., Howell A.M., Salo T.P., Ragland J.D., MacDonald A.W., III, Gold J.M., Silverstein S.M., Barch D.M., Carter C.S. (2017). Functional network changes and cognitive control in schizophrenia. Neuroimage Clin., 15, 161-170. PMCID: PMC5429248. [CNTRACS]

2016

Abram, S.V., Helwig, N., Moodie, C.A., DeYoung C.G., MacDonald, A.W., III, Waller, N.G. (2016). Bootstrap Enhanced Penalized Regression for Variable Selection with Neuroimaging Data. Frontiers of Neuroscience, 10, 344. PMID: 27516732

Abram, S. V., Wisner, K. M., Fox, J. M., Barch, D. M., Wang, L., Csernansky, J. G., MacDonald, A. W., & Smith, M. J. (2016). Fronto-temporal connectivity predicts cognitive empathy deficits and experiential negative symptoms in schizophrenia. Human Brain Mapping, 38(3), 1111-1124. PMID: 27774734

Atluri, G., MacDonald, A.W., III, Lim, K., Kumar, V. (2016). Studying Brain Networks Using Functional Imaging Data. IEEE Computer.

Blackman, R., Crowe, D., DeNicola, A., Sakellaridi, S., MacDonald, A.W., III, & Chafee, M.V. (2016). Monkey prefrontal neurons reflect logical operations for cognitive control in a variant of the AX continuous performance task (AX-CPT). Journal of Neuroscience. PMID: 27053213

MacDonald, A.W., III, Zick, J.I., Chafee, M.V., Netoff, T.I. (2016). Integrating insults: Using fault tree analysis to guide schizophrenia research across levels of analysis. Frontiers of Human Neuroscience, 9, 698. PMID: 26779007

Miner, M.H, Romine, R.S., Raymond, N., Janssen, E., MacDonald, A.W., III, Coleman, E. (2016). Understanding the Personality and Behavioral Mechanisms Defining Hypersexuality in Men Who Have Sex with Men. Journal of Sexual Medicine, 13, 1323-1331. PMID: 27486137

Nienow, T.M., MacDonald, A.W., III, Lim, K.O. (2016). TDCS Produces Incremental Gain When Combined with Working Memory Training in Patients with Schizophrenia: A Proof of Concept Pilot Study. Schizophrenia Research, 172, 218-219. PMID: 26852404

Poppe, A.B., Barch, D.M., Carter, C.S., Gold, J.M., Ragland, J.D., Silverstein, S.M., MacDonald, A.W., III. (2016). Reduced Frontoparietal Activity in Schizophrenia is Linked to a Specific Deficit in Goal Maintenance: a Multi-site Functional Imaging Study. Schizophrenia Bulletin, 42, 1149-57. PMID: 27060129 [CNTRACS]

2015

Abram, S.V., Breton, Y-A, Schmidt, B., Redish, A.D., & ,b>MacDonald, A.W., III. (2015). The Web-Surf Task: a translational model of human decision-making. Cognitive, Affective and Behavioral Neuroscience, 16, 37–50. PMID: 26377334

Abram, S.V., Wisner, K.M., Grazioplene, R.G., Krueger, R.F., MacDonald, A.W., III, DeYoung, C.G. (2015). Functional coherence of insula networks is associated with externalizing behavior. Journal of Abnormal Psychology, 124, 1079-91. PMID: 26301974

Atluri, G., Steinbach, M., Lim, K.O, Kumar, V., & MacDonald, A.W., III (2015). Discriminative subnetworks in schizophrenia revealed using connectivity cluster analysis. Human Brain Mapping. PMID: 25394864

Elshaikh, A., Sponheim, S.R., Chafee, M., MacDonald, A.W., III (2015). Spatial attentional control is not impaired in schizophrenia: Dissociating specific deficits from generalized impairments. Journal of Abnormal Psychology, 124(2), 302-8. PMID: 25546021

Gu, L., Lim, K.O., Specker, S., Raymond, N., & MacDonald, A.W., III (2015). Valuation of reward in long-term stimulant abuse: the specificity of decision-making biases in cocaine addiction but not binge eating disorder. Acta Psychopathologica, 1, 1-11. DOI: 10.4172/2469-6676.10007.

Lopez-Garcia, P., Lesh, T.A., Taylor, S., Barch, D.M., MacDonald, A.W., III, Gold, J.M., Ragland, J.D., Strauss, M., Silverstein, S.M., Carter, C.S. (2015). The neural circuitry supporting goal maintenance during cognitive control: a comparison of Expectancy AX-CPT and Dot Probe Expectancy Paradigms. Cognitive, Affective and Behavioral Neuroscience. PMID: 26494483 [CNTRACS]

Poppe, A.B, Carter, C.S., Minzenberg, M.J., MacDonald, A.W., III. (2015). Task-based functional connectivity as an indicator of genetic liability to schizophrenia. Schizophrenia Research, 162, 118–123. PMID: 25592803

Ragland, J.D., Ranganath, C, Harms, M.P., Barch, D.M., Gold, J.M, Layher, E., Lesh, T.A., MacDonald, A.W., III, Niendam, T.A., Phillips, J., Silverstein, S.M., Yonelinas, A.P., & Carter, C.S. (2015). Functional and neuroanatomical specificity of episodic memory dysfunction in schizophrenia: an fMRI study of the relational and item-specific encoding task. JAMA: Psychiatry, 72(9), 909-16. PMID: 26200928 [CNTRACS]

Ramsay, I.S. & MacDonald, A.W., III (2015). Brain correlates of cognitive remediation in schizophrenia: activation likelihood analysis shows preliminary evidence of neural target engagement. Schizophrenia Bulletin, 41(6), 1276-84. PMID: 25800249

Sheffield, J.M., Repovs, G., Harms, M.P., Carter, C.S., Gold, J.M, MacDonald, A.W. III, Ragland, J. D., Silverstein, S.M, Godwin, D., Barch, D.M. (2015). Evidence for Accelerated Decline of Functional Brain Network Efficiency in Schizophrenia. Schizophrenia Bulletin. PMID: 26472685 [CNTRACS]

Sheffield, J.M., Repovs, G., Harms, M.P., Carter, C.S., Gold, J.M, MacDonald, A.W. III, Ragland, J. D., Silverstein, S.M, Godwin, D., Barch, D.M. (2015). Fronto-parietal and cingulo-opercular network integrity and cognition in health and schizophrenia. Neuropsychologia, 73, 82-93. PMID: 25979608 [CNTRACS]

Silverstein, S.M., Harms, M.P., Carter, C.S., Gold, J.M., Keane, B.P., MacDonald, A.W., III, Ragland, J.D., & Barch, D.M. (2015). Cortical contributions to impaired contour integration in schizophrenia. Neuropsychologia, 75, 469-80. PMID: 26160288 [CNTRACS]

2014

Camchong, J., MacDonald A.W., III, Mueller, B.A., Nelson, B. Specker, S., Lim, K.O. (2014). Changes in resting functional connectivity during abstinence in stimulant use disorder: a preliminary comparison of relapsers and abstainers. Drug & Alchohol Dependence, 39, 145-51. PMID: 24745476

Goghari, V., MacDonald, A.W., III, Sponheim, S.R. (2014). Relationship between prefrontal grey matter volumes and working memory performance in schizophrenia: a family study. Schizophrenia Research, 153(1-3), 113-21. PMID: 24529364

Moodie, C.A., Wisner, K.M., MacDonald, A.W., III (2014). Characteristics of canonical intrinsic connectivity networks across tasks and monozygotic twin pairs. Human Brain Mapping. PMID: 24984861

Seo, D., Olman, C.A., Haut, K.M., Sinha, R., & MacDonald, A.W., III, Patrick, C.J. (2014). Neural correlates of preparatory and regulatory control over positive and negative emotion. Social, Cognitive and Affective Neuroscience, 9, 494-504. PMID: 23887812

Sheffield, J., Gold, J., Strauss, M., Carter, C., MacDonald, A.W. III, Ragland, D., Silverstein, S., Barch, D. (2014). Common and specific cognitive deficits in schizophrenia: relationships to function. Cognitive, Affective and Behavioral Neuroscience, 14(1), 161-74. PMID: 24037621

Strauss, M.E., McLouth, C., Barch, D.M., Carter, C.S., Gold, J.M., Luck, S.J., MacDonald, A.W., III, Ragland, J.D., Ranganath, C., Keane, B.P., Silverstein, S.M. (2014). Temporal stability and moderating effects of age and gender on CNTRaCS task performance. Schizophrenia Bulletin, 40, 835-844. PMID: 23817024 [CNTRACS]

2013

Atluri, G., Padmanabhan, K., Fang, G., Steinbach, M., Petrella, J.R., Lim, K., MacDonald, A.W., III, Samatova, N.F., Doraiswamy, P.M., Kumar, V. (2013). Complex biomarker discovery in neuroimaging data: finding a needle in a haystack. Neuroimage: Clinical, 3, 123-131. PMID: 24179856

Blackman, R.K., MacDonald, A.W., III, Chafee, M.V. (2013). Effects of ketamine on context-processing performance in monkeys: a new animal model of cognitive deficits in schizophrenia. Neuropsychopharmacology, 38, 2090-2100. PMID: 23660706

Crowe, D.A., Goodwin, S.J., Blackman, R.K., Sakellaridi, S., Sponheim, S.R., MacDonald, A.W., III, Chafee, M.V. (2013). Prefrontal neurons transmit signals to parietal neurons that reflect executive control of cognition. Nature Neuroscience, 16, 1484-91. PMID: 23995071

Erickson, K.I., Banducci, S.E., Weinstein, A.M., MacDonald, A.W., III, Ferrell, R.E., Halder, I, Flory, J.D., Manuck, S.B. (2013). The brain-derived neurotrophic factor Val66Met polymorphism moderates an effect of physical activity on working memory performance. Psychological Science, 24, 1770–1779. PMID: 23907543

Jones, J.A.H., Lim, K.O., Wozniak, J.R., Specker, S., MacDonald, A.W., III (2013). Context-processing abilities in chronic cocaine users. Psychology of Addictive Behaviors, 27(3):687-95. PMID: 23586455

Owoso, A., Barch, D.M., Carter, C.S., Gold, J., MacDonald, A.W.,III, Ragland, J.D., Silverstein, S., Strauss, M.E. (2013). Cognition in schizophrenia and schizoaffective disorder: impairments that are more similar than different. Psychological Medicine. 43, 2535-45. PMID: 23522057

Patzelt, E.H., Kurth-Nelson, Z., Lim, K.O., MacDonald, A.W., III (2013). Excessive state switching underlies reversal-learning deficits in cocaine users. Drug and Alcohol Dependence, 39, 403-13. PMID: 24176201

Poppe, A., Wisner, K., Atluri, G., Lim, K.O., Kumar, V., MacDonald, A.W., III (2013). Toward a neurometric foundation for probabilistic independent component analysis of fMRI data. Cognitive, Affective and Behavioral Neuroscience, 13, 641–659. PMID: 23836423

Ramsay, I. S., Yzer, M.C., Luciana, M., Vohs, K.D., MacDonald, A.W., III (2013). The involvement of socio-emotional and executive brain networks in the processing of persuasive anti-drug messages. Journal of Cognitive Neuroscience, 25, 1136-47. PMID: 23530896

Wisner, K.M., Atluri, G., Lim, K.O., MacDonald, A.W., III (2013). Neurometrics of intrinsic connectivity networks at rest using fMRI: Retest reliability and cross validation using a meta-level method. NeuroImage, 76, 236-251. PMID: 23507379

Wisner, K.M., Patzelt, E. H., Lim, K.O., MacDonald, A.W., III (2013). An intrinsic connectivity network approach to insula-derived dysfunctions among cocaine users. American Journal of Drug and Alcohol Addiction, 76. 236-251. PMID: 24200210

2012

Barch, D.M., Carter, C.S., Dakin, S.C., Gold, J., Luck, S.J., MacDonald, A.W., III, Ragland, J.D., Silverstein, S.M., Strauss, M.E. (2012). The clinical translation of a measure of gain control: the contrast-contrast effect task. Schizophrenia Bulletin, 38, 135-143. PMCID: 3245599 [CNTRACS]

Carter C.S., Minzenberg M., West R., MacDonald A.W., III (2012). CNTRICS imaging biomarker selections: Executive control paradigms. Schizophrenia Bulletin, 38, 34-42. PMID:22114099

Gold, J.M., Barch, D.M., Carter, C.S., Dakin, S., Luck, S.J., MacDonald, A.W., III, Ragland, J.D., Ranganath, C., Silverstein, S.M., Strauss, M.E. (2012). Clinical, functional and inter-task correlations of measures developed by the Cognitive Neuroscience Test Reliability and Clinical applications for Schizophrenia (CNTRACS) consortium. Schizophrenia Bulletin, 38, 144-152. PMCID: 3245578 [CNTRACS]

Henderson, D., Poppe, A., Barch, D.M., Carter, C.S., Gold, J.M., Ragland, J.D., Silverstein, S.M., Strauss, M.E., MacDonald, A.W., III (2012). Optimization of a goal maintenance task for use in clinical applications. Schizophrenia Bulletin, 38, 104–113. PMCID: 3245586 [CNTRACS]

Keane, B.P., Silverstein, S.M., Barch, D.M., Carter, C.S., Gold, J.M., Kovács, I, MacDonald, A.W., III, Ragland, J.D., Strauss, M.E. (2012). The spatial range of contour integration deficits in schizophrenia. Experimental Brain Research, 220, 251-259. PMID: 22710617 [CNTRACS]

Ragland, J.D., Ranganath, C., Barch, D. M., Gold, J.M., Haley, B., MacDonald, A.W, III, Silverstein, S. M., Strauss, M.E., Yonelinas, A.P., Carter, C.S. (2012). Relational and Item-Specific Encoding (RISE): Task development and psychometric characteristics. Schizophrenia Bulletin, 38, 114-124. PMCID: 3245591 [CNTRACS]

Silverstein, S.M., Keane, B.P., Barch, D.M., Carter, C.S., Gold, J.M., Kovacs, I., MacDonald, A.W., III, Ragland, J.D. (2012). Optimization and validation of a visual integration test for schizophrenia research. Schizophrenia Bulletin, 38, 125-134. PMID: 22021658 [CNTRACS]

Taylor, S.F., & MacDonald, A.W., III. (2012). Brain mapping biomarkers of socio-emotional processing in schizophrenia. Schizophrenia Bulletin, 38, 73-80. PMCID: 3245598

2011

Camchong, J., MacDonald, A.W., III, Bell, C., Mueller, B.A., Lim, K.O. (2011). Altered functional and anatomical connectivity in schizophrenia. Schizophrenia Bulletin, 37, 640-650. PMCID: 3080691

Camchong, J., MacDonald, A.W., III, Nelson, B., Bell, C., Mueller, B.A., Specker, S., Lim, K.O. (2011). Frontal hyperconnectivity related to delayed discounting and reversal learning task performance in cocaine subjects. Biological Psychiatry, 69, 1117-1123. PMCID: 3090521

Goghari, V., MacDonald, A.W., III, Sponheim, S.R. (2011). Temporal lobe structures and facial emotion recognition in schizophrenia patients and non-psychotic relatives. Schizophrenia Bulletin, 37, 1281-1284. doi: 10.1093/schbul/sbq046 PMCID: 3196942

Kang, S.S., Sponheim, S.R., Chafee, M.V., & MacDonald, A.W., III (2011). Disrupted functional connectivity for controlled visual processing as a basis for impaired spatial working memory in schizophrenia. Neuropsychologia, 49, 2836– 2847. PMCID: 3156358

Yzer, M.C., Vohs, K.D., Luciana, M., Cuthbert, B.N., & MacDonald, A.W., III (2011). Affective antecedents of the perceived effectiveness of antidrug advertisements: an analysis of adolescents’ momentary and retrospective evaluations. Prevention Science, 12, 278-288. PMID: 21499729

2010

Goghari, V., Sponheim, S.R., MacDonald, A.W., III (2010). The functional neuroanatomy of symptom dimensions in schizophrenia: A qualitative and quantitative review of a persistent question. Neuroscience & Biobehavioral Reviews, 34, 468-486. PMCID: 2813961

Haut, K.M., Lim, K.O., MacDonald, A.W., III (2010). Prefrontal cortical changes following cognitive training in patients with chronic schizophrenia: effects of practice, generalization and specificity. Neuropsychopharmacology, 35, 1850-1859. Featured on MDLinx.com; NPP “Top Ten” download list. PMCID: 3055638

Haut, K.M., MacDonald, A.W., III (2010). Persecutory delusions and the perception of trustworthiness in unfamiliar faces in schizophrenia. Psychiatry Research, 178, 456-60. PMID: 20569994

Jones, J.A.H., Sponheim, S.R., MacDonald, A.W., III (2010). The dot pattern expectancy (DPX) task: reliability and replication of deficits in schizophrenia. Psychological Assessment, 22, 131-141. PMID: 20230159

Kang, S.S. & MacDonald, A.W., III (2010). Limitations of true score variance to measure discriminating power: Psychometric simulation study. Journal of Abnormal Psychology, 119, 300-306. PMCID: 2869469

2009

Barch, D.M., Berman, M.G., Engle R., Jones, J.A.H., Jonides, J., MacDonald, A.W., III, Nee, D.E., Redick, T.S., Sponheim, S.R. (2009). CNTRICS final task selection: working memory. Schizophrenia Bulletin, 35, 136-152. PMCID: 2643954

Camchong, J., Lim, K.O., Sponheim, S.R., MacDonald, A.W., III (2009). Frontal white matter integrity as an endophenotype for schizophrenia: Diffusion tensor imaging in monozygotic twins and patients’ nonpsychotic relatives. Frontiers in Human Neuroscience, 3 1-6. Included in ebook: An Update On Neurocognitive Impairment in Schizophrenia and Depression, K. Hugdahl & V.D. Calhoun (Eds.). PMCID: 2773169

Goghari, V. & MacDonald, A.W., III (2009). The neural basis of cognitive control: response selection and inhibition. Brain & Cognition, 71, 72-83. PMCID: 290505

Johnson, M.K., Rustichini, A., MacDonald, A.W., III (2009). Suspicious personality predicts behavior on a social decision-making task. Personality and Individual Differences, 47, 30-35. DOI: 10.1016/j.paid.2009.01.050

MacDonald, A.W., III & Kang, S.S. (2009). Misinterpreting schizophrenia relatives’ impairments. American Journal of Medical Genetics B: Neuropsychiatric Genetics, 150B, 443-444. PMID: 18561246

MacDonald, A.W., III & Schulz, S.C. (2009). What we know: findings that every theory of schizophrenia should explain. Schizophrenia Bulletin, 3, 493–508. Translated into Spanish in Schizophrenia Bulletin, Spanish excerpted Edition. PMCID: 2669587

MacDonald, A.W., III, Thermenos, H.W., Barch, D.M., & Seidman, L.J. (2009). Imaging genetic liability to schizophrenia: A systematic review of fMRI studies of patients’ non-psychotic relatives. Schizophrenia Bulletin, 35, 1142-1162. PMCID: 2762618

Selected Older Publications

MacDonald, A.W., III (2008). Building a clinically-relevant cognitive task: Case study of the AX paradigm. Schizophrenia Bulletin, 34, 619-628. PMID: 18487225

Snitz, B.E., MacDonald, A.W., III, Carter, C.S. (2006). Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: A meta-analytic review of putative endophenotypes. Schizophrenia Bulletin, 32, 179-194. PMCID: 16166612

MacDonald, A.W., III, Goghari, V.M., Hicks, B.M., Flory, J.D., Carter, C.S., Manuck, S.B. (2005). A convergent-divergent approach to context processing, general intellectual, functioning, and the genetic liability to schizophrenia. Neuropsychology, 19, 814-821. PMID: 16351357

Kerns, J.G., Cohen, J.D., MacDonald, A.W., III, Cho, R.Y., Stenger, V.A., & Carter, C.S. (2004). Anterior cingulate conflict monitoring and adjustments in control. Science, 303, 1023-1026. PMID: 14963333

MacDonald, A.W., III, Pogue-Geile, M.F, Johnson, M.K. & Carter, C.S (2003). A specific deficit in context processing in the unaffected siblings of patients with schizophrenia. Archives of General Psychiatry, 60, 57-65. PMID: 12511173

MacDonald, A.W., III, Cohen, J.D., Stenger, V.A., & Carter, C.S. (2000). Dissociating the role of the dorsolateral prefrontal cortex and anterior cingulate cortex in cognitive control. Science, 288, 1835-1838. PMID: 10846167

Carter, C.S., MacDonald, A.W., III, Botvinick, M., Ross, L.L., Stenger, V.A., Noll, D. & Cohen, J.D. (2000). Parsing executive processes: strategic versus evaluative functions of the anterior cingulate cortex. Proceedings of the National Academy of Sciences, 97, 1944-1948. PMID: 10677559